Tfrc hif
Web1 Jun 2024 · Differential gene expression of (D) HIF1A and (E) TFRC in ileal biopsies from non-inflamed (blue dots) and inflamed (red dots) areas, according to iron deficiency status of IBD patients at moment ... WebDisease relevance of Tfrc. On the contrary, increased transcription of the TfR gene in isolated nuclei was observed during reperfusion; during the ischemic phase this was preceded by enhanced binding of hypoxia inducible factor (HIF-1) to a DNA sequence derived from the TfR promoter .
Tfrc hif
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Web1 May 2024 · HIF-1α, TFRC-1 and TIM-2 gene expressions were investigated in both brain and heart tissue by RT-PCR method. As a result of the data, TIM-2 expression significantly decreased in the brain (p. 0.01) and cardiac ventricle tissue (p0.05) in female rats. TFRC-1 gene expression decreased in female brain tissue (p0.05). Our findings suggest that ... WebIn addition, the transferrin receptor gene (TFRC) is also a target common to both MYC and HIF 73,74. TFRC could also be inhibited by small molecules, leading to growth inhibition …
Web12 Sep 2024 · We also confirmed similar effects of ISCA2 knockdown in decreasing HIF-1/2α, IRP1, IRP2 and TFRC in RCC4 cells which are pVHL deficient, suggesting that ISCA2 … Web1 Dec 2014 · HIF-1 and HIF-2 regulate gene transcription in a cell type-specific and microenvironment context dependent manner ... In addition, TFGB1, TFRC, IL1B and CCL5 …
WebFurther, we identified the MYC proto-oncogene protein as a second CPSF1 substrate and show that active ABL kinase protects MYC from CPSF1-mediated degradation. These … Web23 Jan 2024 · Background Transferrin receptor 1 (TfR1), encoded by TFRC, is a key regulator of iron homeostasis and plays important roles in many diseases, including cancers. …
WebSYSTEMIC IRON DEFICIENCY AND INTESTINAL INFLAMMATION CONTROL GUT MUCOSAL HIF-1? AND TFRC ACTIVATION IN INFLAMMATORY BOWEL DISEASE Arno R. Bourgonje 1 …
WebClinical data analysis showed that high TFRC expression in cervical cancers was associated with incrementally advanced stage, tumor status, and lymph nodes (all p-values <0.05), … even whole numbers less than 12WebSystemic iron deficiency and intestinal inflammation control gut mucosal HIF-1α and TFRC activation in inflammatory bowel disease — the University of Groningen research portal Systemic iron deficiency and intestinal inflammation control gut mucosal HIF-1α and TFRC activation in inflammatory bowel disease brother wb3000Web21 Mar 2024 · TFRC (Transferrin Receptor) is a Protein Coding gene. Diseases associated with TFRC include Immunodeficiency 46 and Combined Immunodeficiency.Among its … evenwichtsbal fysioWebG@ Bð% Áÿ ÿ ü€ H FFmpeg Service01w ... even wikran andreassenWebTFRC involved in several pathways and played different roles in them. We selected most pathways TFRC participated on our site, such as HIF- signaling pathway, Endocytosis, Phagosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with TFRC were listed below. even whole number that is a square numberWebThe HIF1α pathway agonist DMOG increased TFRC expression in Caco-2 cells, which was blunted in HIF1A-null cells.Conclusion: We demonstrate that inflammation and anatomical location primarily determine HIF1α pathway activation and downstream TFRC expression in the intestinal mucosa. IBD patients with ID may benefit from treatment with HIF1α ... even whyWebIn addition, the transferrin receptor gene (TFRC) is also a target common to both MYC and HIF 73,74. TFRC could also be inhibited by small molecules, leading to growth inhibition 75,76. even whole numbers less than 9