2024 Glut3 molecular weight

Glut3 molecular weight

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August undefined, 2024

WebMay 12, 2024 · Phase was solved by molecular replacement using PHASER 44 with the structure of GLUT3 (PDB code: 4ZW9) as a searching model. The model was rebuilt in COOT 45 and refined with PHENIX 46 . WebJul 15, 2015 · The crystals of GLUT3 in the presence of d-glucose were obtained in the P2 1 Fig. 1c, Extended Data Fig. 2a–d and Extended Data Table 1). The transmembrane …

Glucose transporter 3 is a rab11-dependent trafficking cargo and …

WebGLUT3 is one of fourteen facilitative sugar transporters, which use the glucose diffusion gradient to move across various plasma membranes to display various specificities, ... WebApr 12, 2024 · Background: The annual prevalence of gestational diabetes mellitus—characterized by an increase in blood glucose in pregnant women—has been increasing worldwide. The goal of this study was to evaluate the expression of glucose transporter 1 (GLUT1) and glucose transporter 3 (GLUT3) in the … john deere gator rack and pinion

GLUT1 antibody (66290-1-Ig) Proteintech - ptglab

WebMay 25, 2024 · The membrane was cut before it was hybridized with GLUT3 antibody according to molecular weight of GLUT3. Raw images of the blots are presented in Supplementary Fig. 3 . WebIn this study, we have demonstrated that in rat brain, GLUT3 is found exclusively in the neuronal/glial fraction and is absent from cerebral microvessels, whereas GLUTl is detected as different molecular weight forms in each fraction. WebMar 9, 2024 · The mouse GLUT3 gene encodes a 493-amino acid protein with a predicted molecular weight of ∼54 kDa, and in this study GLUT3 was detected at ∼66 kDa in mouse sciatic nerve and muscle (Supplementary Fig. 2B). john deere gator promotions

GLUT3 antibody (20403-1-AP) Proteintech - ptglab

Glut1 (D3J3A) Rabbit mAb Cell Signaling Technology

WebGLUT3 was detected in the syncytiotrophoblast at all gestational ages by immunohistochemistry. Using Western blotting GLUT3 was detected as an integral membrane protein at a molecular weight of ~50kDa in microvillous membranes from all trimesters but not in syncytial basal membranes. WebMar 21, 2024 · We found that the glucose transporter GLUT3 is essential for the effector functions of Th17 cells in models of autoimmune colitis and encephalomyelitis. At the molecular level, we show that GLUT3-dependent glucose uptake controls a metabolic-transcriptional circuit that regulates the pathogenicity of Th17 cells. intensive driving courses kentWebSep 2, 2024 · Under glucose-limiting conditions, GLUT3 expedited CRC cell growth by accelerating glucose input and fuelling nucleotide synthesis. Notably, GLUT3 had a greater impact on cell growth than GLUT1 under glucose-limiting stress. Mechanistically, low-glucose stress dramatically upregulated GLUT3 via the AMPK/CREB1 pathway. intensive driving courses in bristol

"WebJan 26, 2024 · The identified GLUT3 inhibitors had IC 50 values between ~ 7 and 38 µM for GLUT3 (Fig. 2, Table 2), and between ~ 6 and 25 µM in GLUT3 S66Y (Supplementary … " - Glut3 molecular weight

Glut3 molecular weight

WebOct 31, 2024 · We created a neural-specific conditional murine glut3 ( Slc2A3 ) deletion ( glut3 flox/flox/nestin-Cre+) to examine the effect of a lack of Glut3 on neurodevelopment. Compared with age-matched glut3 flox/flox = WT and heterozygotes ( glut3 flox/+/nestin-Cre+), we found that a >90% reduction in male and female brain Glut3 occurred by … WebCalculated molecular weight: 492 aa, 54 kDa: Observed molecular weight: 45-55 kDa: GenBank accession number: BC121804: Gene symbol: SLC2A1: Gene ID (NCBI) 6513: Conjugate: Unconjugated: Form: Liquid: …

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WebImmunoblots of brain membrane preparations showed that both antisera identified peptide-inhibitable protein bands of molecular weight 45,000-50,000. Immunocytochemical studies demonstrated that binding sites for these antisera were abundantly distributed in neuropil in all brain regions. Web1-氧杂-8-氮杂-螺[4,5]癸-3-酮1-Oxa-8-aza-spiro[4.155.19432133382-42-...

WebApr 6, 2024 · GLUT3 expression is reported in monocytes and T lymphocytes in the human immune system , and in activated T lymphocytes in ... As previously reported we noted that GLUT3 protein aggregates to form high molecular weight smears in Western blot of boiled lysate and that copy number dependent protein levels at 54 kDa could only be observed … WebNational Center for Biotechnology Information

Web康朗生物为您提供脑钠通道蛋白2抗体的参数及2024年最新报价，厂家专业的脑钠通道蛋白2抗体售后服务团队，是您值得信赖的 ... WebGlutor is a potent inhibitor of glucose uptake that targets glucose transporters GLUT1, -2, and -3. Inhibition of glucose uptake by glutor leads to upregulation of GLUT3 and GLUT1 …

WebJan 26, 2024 · These were tested for in vivo inhibition of GLUT3 expressed in hexose transporter-deficient yeast cells, resulting in six new GLUT3 inhibitors. Examining their specificity for GLUT1-5 revealed that the most potent GLUT3 inhibitor (G3iA, IC 50 ~ 7 µM) was most selective for GLUT3, inhibiting less strongly only GLUT2 (IC 50 ~ 29 µM). …

WebApr 5, 2024 · GLUT3 controls the effector function of Th17 cells. To investigate the function of GLUT3 in T cells, we generated mice with T cell-specific inactivation of the Slc2a3 gene by crossing Slc2a3 fl/fl mice (Fidler et al., 2024) with Cd4 Cre animals. We first verified that GLUT3 expression was abolished in CD4 + T cells without a compensatory upregulation … john deere gator side tool rackWebGlut3 Antibody (M-20) has been replaced by a more specific monoclonal antibody, Glut3 (G-5) that provides a stronger signal & more reproducible data. ... 5 by JM from Well defined band observed at expected molecular Well defined band observed at expected molecular weight by Western Blot using EOC 20 whole cell lysate. -SCBT QC. Date published ... john deere gator plow mountWebJun 1, 2024 · GLUT3 expression is reported in monocytes and T lymphocytes in the human immune system , and in activated T lymphocytes in ... As previously reported we noted that GLUT3 protein aggregates to form high molecular weight smears in Western blot of boiled lysate and that copy number dependent protein levels at 54 kDa could only be observed … john deere gator safety trainingWebMolecular Weight of Glut3: 48-70 kDa. Positive Controls: Hep G2 cell lysate: sc-2227 or U-87 MG cell lysate: sc-2411. Alexa Fluor STORAGE Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. No MSDS required. SELECT PRODUCT CITATIONS 1. Lin, C.C., et al. 2012. intensive driving courses leicestershireWebAug 1, 2008 · Neuronal GLUT3 and Cerebral Glucose Utilization. Numerous studies, predominantly in rodent brain, concluded that glucose delivery … john deere gator shock replacementWebKey features and details Expression system: Wheat germ Suitable for: SDS-PAGE, WB, ELISA You may also be interested in Primary Anti-Glucose Transporter GLUT3 antibody (ab15311) Primary Anti-Glucose Transporter GLUT3 + GLUT14 antibody [EPR10508 (N)] - N-terminal (ab191071) Primary Anti-Glucose Transporter GLUT3 antibody (ab41525) intensive driving courses livingstonWebJun 22, 1998 · Western blot analysis of the rat brain revealed that the antiserum detected a strong band with a molecular weight of 45 kDa and a weak band of about 55 kDa, which corresponded respectively to the known molecular weights of the GLUT1 proteins in the brain parenchymal cells and the brain microvessels. john deere gator seat covers sale