2024 Fsip1 regulates autophagy in breast cancer

Fsip1 regulates autophagy in breast cancer

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WebAug 2, 2013 · Aim: The study aimed to identify and characterize highly specific breast tumor biomarkers. Methods: A microarray data set comprised of 513 diverse normal and tumor mRNA samples was analyzed to identify breast tumor biomarkers with minimal expression in normal tissues. Results:FSIP1 was identified as a breast tumor biomarker with … WebFSIP1 regulates autophagy in breast cancer Caigang Liu, Lisha Sun, Jie Yang, Tong …

FSIP1 regulates autophagy in breast cancer (Q90226233)

WebJan 28, 2024 · Accumulating evidence indicated that autophagy promoted cancer survival and mediated resistance to anticancer therapies such as ... MTA1 is a novel regulator of autophagy that induces tamoxifen resistance in breast cancer cells. Autophagy, 14 (2024), pp ... FSIP1 regulates autophagy in breast cancer. Proc. Natl. Acad. Sci. U. S. … WebJul 3, 2024 · Fibrous sheath interacting protein 1 (FSIP1) has recently been identified as … sub array with sum equal to zero

Over-expression of FSIP1 promotes breast cancer …

WebJul 1, 2024 · Downregulation of FSIP1 promotes autophagy, and attenuates … WebJan 11, 2024 · Additionally, autophagy seems to exert a dual role in luminal breast cancer, and also triple-negative BC . Takabe et al. demonstrated that high NRF2 tumors were associated with high infiltration of DCs by conducting in silico analyses in 5,443 breast cancer patients from several large patient cohorts . Besides, it is likely that different ... WebThe sensitivity of cells to chemotherapeutic agents has a major effect on disease outcome in breast cancer patients. Unfortunately, there are numerous factors involved in the regulation of chemosensitivity, and the mechanisms need to be further investigated. Autophagy/Beclin 1 regulator 1 (Ambra1) i … sub array with zero sum

FSIP1 regulates autophagy in breast cancer PNAS

Role and mechanism of autophagy‐regulating ... - Wiley Online Library

Web2.5. Autophagy Influences Tumor Dormancy in Breast Cancer. When the environment … WebNov 1, 2024 · Autophagy plays multiple and often disparate roles during different stages of tumorigenesis and in response to anti-tumor treatments; in fact, autophagy is induced by almost all conventional treatments of breast cancer and is considered a target for pharmacologic blockade in the clinic. Consequently, it is important to further our … painful knot on back of heelWebApr 1, 2015 · Results. Expression of FSIP1 protein was significantly higher in breast cancer tissues compared to tumor-adjacent tissues (p = 0.001).Strong correlation was observed between FSIP1 expression and human epidermal growth factor receptor 2 (Her-2) or Ki67 expression in breast cancer (p = 0.027 and 0.002, respectively).Similarly, serum level of … subaru $500 off coupon

"WebNov 30, 2016 · Furthermore, B7-H3 regulates glucose metabolism in breast cancer cells , suggesting that the B7-H superfamily, to which PD-L1 and B7-H3 belong or the immunoglobulin superfamily to which these and PD-1 all belong , could have important tumor metabolic effects, which is an area meriting additional investigations. Our RNA-seq … " - Fsip1 regulates autophagy in breast cancer

Fsip1 regulates autophagy in breast cancer

Elevated expression of cancer/testis antigen FSIP1 in ER-positive ...

WebNov 1, 2024 · There is ample evidence that the majority of conventional therapies used to combat breast cancer induce autophagy (Table 1).Although autophagy is most often considered to be a protective mechanism that allows cells to evade apoptosis, it is clear that the nature of autophagy in response to anti-cancer modalities is a complex subject (Fig. … WebFeb 27, 2024 · Recent experiments from our group found that FSIP1 could bind with Her2 and regulate breast cancer growth and invasiveness 6. Other studies have reported that FSIP1 associates with PKA 7 and SRC-3 8, ... FSIP1 regulates autophagy in breast cancer. Liu C, Sun L, Yang J ...

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WebMar 2, 2024 · Macroautophagy (herein referred to as autophagy) is a key homeostatic pathway that facilitates the degradation and recycling of cellular material 1. The benefits of stimulating autophagy in ... WebNov 1, 2024 · Autophagy plays multiple and often disparate roles during different stages …

WebFibrous sheath interacting protein 1 (FSIP1) is a cancer antigen expressed in the majority of breast cancer tissues and is associated with poor prognosis. However, the role of FSIP1 in the progression and drug sensitivity of triple-negative breast cancer (TNBC) has not been explored. Here, we show that FSIP1 deficiency by shRNA-mediated knockdown or … WebFSIP1 knockout in breast cancer cells signiﬁcantly increased their sensitivity to …

WebFibrous sheath interacting protein 1 (FSIP1) has been identified as a poor prognostic indicator of breast cancer. Here, we report that FSIP1 positively regulates the proliferation and invasion of triple-negative breast cancer … WebFeb 27, 2024 · Therefore, we sought to establish a correlation between the clinico-pathological features of breast cancer and FSIP1 expression in breast cancer tissues, as well as to validate its role in tumor progression and chemo-resistance. We analyzed FSIP1 expression in the breast cancer and para-tumor tissues by immunohistochemistry.

WebMay 13, 2024 · Keywords: cancer/testicular antigen, FSIP1, regulation, autophagy in lung cancer cells ... and regulate chromosome segregation to maintain the stability of the microtubule system. At the transcriptional level, most normal tissues do not express it. Due to the tissue specificity of breast cancer and bladder cancer, when FSIPI gene … painful knot on buttockWebApr 25, 2024 · Despite improvements in our understanding of the biology behind triple … painful knot on finger jointWebDec 3, 2024 · Fibrous sheath interacting protein 1 (FSIP1) has been identified as a poor … painful knot in shoulder bladeWebscientific article published on 03 December 2024 subarray with zero sum in javaWebFSIP1 deficiency promoted autophagy, enhanced AMP-activated protein kinase … subaru 0 financing 60 monthsWebDec 3, 2024 · Here, we report that FSIP1 positively regulates the proliferation and … subarticular cystic changeWebFeb 25, 2024 · 2.1. MA Inhibits Breast Cancer Cell Proliferation. To explore the effects of MA (Figure 1 a) on breast cancer cell proliferation, we performed the MTT assay on MCF-10A, MDA-MB-231, and MCF-7 cells at concentrations of 0, 0.5, 1, 2, 4, and 8 μM for 24 h.The results displayed that MA had cytotoxic effects on MDA-MB-231 and MCF-7 cells … painful knot on breast bone